LSM1
Sign in to saveAlso known as CASM, YJL124C, LSM1 homolog, mRNA degradation associated
U6 snRNA-associated Sm-like protein LSm1 is a protein that in humans is encoded by the LSM1 gene.
Gene data
LSM1- Name
- LSM1 homolog, mRNA degradation associated
- Type
- protein-coding
- Position
- 38,161,436–38,176,730 (−)
- Aliases
- CASM, FICUS, YJL124C
- Ensembl
- ENSG00000175324
- RefSeq RNA
- NM_014462.3, NR_045492.2, NR_045493.1
- RefSeq protein
- NP_055277.1
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
U6 snRNA-associated Sm-like protein LSm1 is a protein that in humans is encoded by the LSM1 gene.
== Function ==
Excerpted from Wikipedia’s “LSM1” article, available under the CC BY-SA 4.0 licence.