malatione

Also known as Cythion, Ovide, Organoderm, Prioderm, Diethyl (dimethoxyphosphinothioylthio)succinate, Carbophos, Karbofos, [(Dimethoxyphosphinothioyl)thio]butanedioic acid diethyl ester

farmaco

In the Vinony graph

Within Vinony's link graph, malatione is referenced by 698 other articles, and connects out to botulinum toxin group, carbamate and acaricide.

It sits within the topics Acetylcholinesterase inhibitors, Antiparasitic agents and Chembox having GHS data.

Its subject is documented across 31 Wikipedia language editions.

Chemical data

Formula: C10H19O6PS2
Molecular weight: 330.4 g/mol
IUPAC name: diethyl 2-dimethoxyphosphinothioylsulfanylbutanedioate
SMILES: CCOC(=O)CC(C(=O)OCC)SP(=S)(OC)OC
InChIKey: JXSJBGJIGXNWCI-UHFFFAOYSA-N
XLogP: 2.4
Polar surface area: 128 Å²
H-bond donors: 0
H-bond acceptors: 8
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 1982
Admin. routes: topical
Indications: parasitic infection, lice infestation

via ChEMBL · EBI

Research

4,896 papers

Malathion poisoning.Ethiopian medical journal · 1971
Malathion for head lice and scabies: treatment and safety considerations.Journal of drugs in dermatology : JDD · 2009
Malathion induced cancer-linked gene expression in human lymphocytes.Environmental research · 2020
Organophosphate toxicity: updates of malathion potential toxic effects in mammals and potential treatments.Environmental science and pollution research international · 2020
Microbial degradation of an organophosphate pesticide, malathion.Critical reviews in microbiology · 2014

via PubMed

Wikidata facts

Subclass of: chemical compound
Has part: carbon
Mass: 330.036067
Has use: insecticide

Show 15 more facts

Commons category: Malathion
chemical formula: C₁₀H₁₉O₆PS₂
vapor pressure: 0.00004
NIOSH Pocket Guide ID: 0375
density: 1.21
immediately dangerous to life or health: 250
melting point: 37
decomposition point: 140
flash point: 325
solubility: 0.02
time-weighted average exposure limit: 15
medical condition treated: lice infestation
canonical SMILES: CCOC(=O)CC(C(=O)OCC)SP(=S)(OC)OC
refractive index: 1.4985
subject has role: carcinogen

Sources (6)

via Wikidata · CC0

Article · Italiano

Il malatione è un insetticida e acaricida organofosfato (fosforoditiodato) parasintomatico che si lega in maniera irreversibile alla colinesterasi, con una tossicità relativamente bassa per l'uomo. In Italia è conosciuto soprattutto come malathion, in URSS era conosciuto come carbofos, in Nuova Zelanda e in Australia come maldisone e in Sudafrica come mercaptotione.

Abstract from DBpedia / Wikipedia · CC BY-SA