MED18
Sign in to saveAlso known as p28b, mediator complex subunit 18, SRB5
Mediator complex subunit 18 (Med18) is a protein that in humans is encoded by the MED18 gene.
Gene data
MED18- Name
- mediator complex subunit 18
- Type
- protein-coding
- Position
- 28,329,002–28,335,976 (+)
- Aliases
- SRB5, p28b
- Ensembl
- ENSG00000130772
- RefSeq RNA
- NM_001127350.2, NM_017638.3, XM_005245914.5, XM_054332155.1, XM_054337204.1
- RefSeq protein
- NP_001120822.1, NP_060108.2, XP_005245971.1, XP_054188130.1, XP_054193179.1
MED18 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008].
Gene Ontology
Biological process
regulation of transcription by RNA polymerase IIpositive regulation of transcription elongation by RNA polymerase IIRNA polymerase II preinitiation complex assemblypositive regulation of transcription initiation by RNA polymerase IIpositive regulation of transcription initiation by RNA polymerase II
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
mediator complex subunit 18
- Symbol
- MED18
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:28,329,002-28,335,976
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- See also
- References
Mediator complex subunit 18 (Med18) is a protein that in humans is encoded by the MED18 gene.
== Function ==
Excerpted from Wikipedia’s “MED18” article, available under the CC BY-SA 4.0 licence.