Structure via PubChem · Public domain (PubChem)
megazol
Sign in to saveAlso known as CL 64855
Megazol (CL 64855) is a nitroimidazole based drug that cures some protozoan infections.
Chemical data
- Formula
- C6H6N6O2S
- Molecular weight
- 226.22 g/mol
- IUPAC name
- 5-(1-methyl-5-nitroimidazol-2-yl)-1,3,4-thiadiazol-2-amine
- SMILES
- CN1C(=CN=C1C2=NN=C(S2)N)[N+](=O)[O-]
- InChIKey
- VDZZTXBMKRQEPO-UHFFFAOYSA-N
- XLogP
- 0
- Polar surface area
- 144 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 226.027294
Show 3 more facts
- chemical formula
- C₆H₆N₆O₂S
- canonical SMILES
- CN1C(=CN=C1C2=NN=C(S2)N)[N+](=O)[O-]
- Commons category
- Megazol
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Megazol (CL 64855) is a nitroimidazole based drug that cures some protozoan infections.
A study of nitroimidazoles found the drug extremely effective against T. cruzi and T. brucei which cause Chagas disease and African sleeping sickness, respectively. The drug is considerably more effective than standard benznidazole therapy (for Chagas) which is considered the gold standard. This is despite that other nitroimidazoles proved ineffective against these pathogens.
Excerpted from Wikipedia’s “megazol” article, available under the CC BY-SA 4.0 licence.