melanocyte-stimulating hormone
Sign in to saveAlso known as MSH, alpha-melanotropin, melanotropins
group of peptide hormones in Homo sapiens
Key facts
- Symbol
- POMC
- Refseq
- NM_000939
- Uniprot
- P01189
- Locus
- Chr. 2 p23
- Structures
- Swiss-model
- Domains
- InterPro
via Wikipedia infobox
Research
8,576 papersvia PubMed
Wikidata facts
- Subclass of
- melanocortins
Show 2 more facts
- found in taxon
- Homo sapiens
- subject has role
- hormone
Sources (3)
via Wikidata · CC0
~6 min read
Encyclopedic overview
The melanocyte-stimulating hormones, known collectively as MSH, also known as melanotropins or intermedins, are a family of peptide hormones and neuropeptides consisting of α-melanocyte-stimulating hormone (α-MSH), β-melanocyte-stimulating hormone (β-MSH), and γ-melanocyte-stimulating hormone (γ-MSH) that are produced by cells in the pars intermedia of the anterior lobe of the pituitary gland.
Synthetic analogues of α-MSH, such as afamelanotide (melanotan I; Scenesse), melanotan II, and bremelanotide (PT-141), have been developed and researched.
Excerpted from Wikipedia’s “melanocyte-stimulating hormone” article, available under the CC BY-SA 4.0 licence.