mycophenolate mofetil

Also known as RS-61443, RS-61443-190, MMF, mycophenolic acid morpholinoethyl ester, 2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate, RS 61443, 2-Morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-hex-4-enoate

chemical compound

Chemical data

Formula: C23H31NO7
Molecular weight: 433.5 g/mol
IUPAC name: 2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
SMILES: CC1=C2COC(=O)C2=C(C(=C1OC)C/C=C(\C)/CCC(=O)OCCN3CCOCC3)O
InChIKey: RTGDFNSFWBGLEC-SYZQJQIISA-N
XLogP: 3.2
Polar surface area: 94.5 Å²
H-bond donors: 1
H-bond acceptors: 8
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 1995
Admin. routes: oral, parenteral
Indications: IGA glomerulonephritis, nephrotic syndrome, pancreatic carcinoma, pemphigus vulgaris

via ChEMBL · EBI

Wikidata facts

Mass: 433.210052
Has use: medication

Show 8 more facts

medical condition treated: membranous glomerulonephritis
chemical formula: C₂₃H₃₁NO₇
route of administration: oral administration
canonical SMILES: CC1=C(C(=C(C2=C1COC2=O)O)CC=C(C)CCC(=O)OCCN3CCOCC3)OC
isomeric SMILES: CC1=C(C(=C(C2=C1COC2=O)O)C/C=C(\C)/CCC(=O)OCCN3CCOCC3)OC
subject has role: DNA polymerase inhibitors
Commons category: Mycophenolate mofetil
legal status (medicine): boxed warning

Sources (4)

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