Also known as IscS, NIFS, HUSSY-08, NFS1 cysteine desulfurase, NFS1, cysteine desulfurase, COXPD52
Cysteine desulfurase, mitochondrial is an enzyme that in humans is encoded by the NFS1 gene.
Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010].
via MyGene.info
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Cysteine desulfurase, mitochondrial is an enzyme that in humans is encoded by the NFS1 gene.
Iron-sulfur clusters are required for the function of many cellular enzymes. The protein encoded by this gene supplies inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded protein belongs to the class-V family of pyridoxal phosphate-dependent aminotransferases.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).