nifurquinazol
Sign in to saveNifurquinazol (NF-1088) is an antibacterial agent of the nitrofuran class. It was never marketed. ==Synthesis== thumb|center|700px|Nifurquinazol synthesis: Treatment of the amide from 5-nitrofuroic acid with phosphorus oxychloride leads to the corresponding nitrile (2). This intermediate is then converted to the iminoether (3) with ethanolic hydrogen chloride. Condensation of anthranilic acid with the iminoether in the presence of sodium methoxide represents another method for preparing quinazolones. The reaction can be visualized as proceeding through the formation of the amidine from additio
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 344.112
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- Commons category
- Nifurquinazol
- chemical formula
- C₁₆H₁₆N₄O₅
- canonical SMILES
- C1=CC=C2C(=C1)C(=NC(=N2)C3=CC=C(O3)[N+](=O)[O-])N(CCO)CCO
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Encyclopedic overview
2 sectionsContents
- Synthesis
- References
{{Drugbox | IUPAC_name = 2,2'-{[2-(5-nitrofuran-2-yl)quinazolin-4-yl]imino}diethanol | image = Nifurquinazol.svg | image_class = skin-invert-image
| tradename = | pregnancy_category = | legal_status = Uncontrolled | routes_of_administration = ?
Excerpted from Wikipedia’s “nifurquinazol” article, available under the CC BY-SA 4.0 licence.