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nitrazine
Sign in to saveNitrazine or phenaphthazine is a pH indicator dye often used in medicine. More sensitive than litmus, nitrazine indicates pH in the range of 4.5 to 7.5. Nitrazine is usually used as the disodium salt.
Chemical data
- Formula
- C16H10N4O11S2
- Molecular weight
- 498.4 g/mol
- IUPAC name
- (3E)-3-[(2,4-dinitrophenyl)hydrazinylidene]-4-oxonaphthalene-2,7-disulfonic acid
- SMILES
- C1=CC(=C(C=C1[N+](=O)[O-])[N+](=O)[O-])N/N=C\2/C(=CC3=C(C2=O)C=CC(=C3)S(=O)(=O)O)S(=O)(=O)O
- InChIKey
- IHRSXGONVFFQQF-SDXDJHTJSA-N
- XLogP
- 1.6
- Polar surface area
- 259 Ų
- H-bond donors
- 3
- H-bond acceptors
- 13
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 497.978749
Show 4 more facts
- chemical formula
- C₁₆H₁₀N₄O₁₁S₂
- canonical SMILES
- C1=CC(=C(C=C1[N+](=O)[O-])[N+](=O)[O-])NN=C2C(=CC3=C(C2=O)C=CC(=C3)S(=O)(=O)O)S(=O)(=O)O
- isomeric SMILES
- C1=CC(=C(C=C1[N+](=O)[O-])[N+](=O)[O-])N/N=C\2/C(=CC3=C(C2=O)C=CC(=C3)S(=O)(=O)O)S(=O)(=O)O
- Commons category
- Nitrazine
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Use
- References
Nitrazine or phenaphthazine is a pH indicator dye often used in medicine. More sensitive than litmus, nitrazine indicates pH in the range of 4.5 to 7.5. Nitrazine is usually used as the disodium salt.
==Use== This test is done to ascertain the nature of fluid in the vagina during pregnancy especially when premature rupture of membranes (PROM) is suspect. This test involves putting a drop of fluid obtained from the vagina onto paper strips containing nitrazine dye. The strips change color depending on the pH of the fluid. The strips will turn blue if the pH is greater than 6.0. A blue strip means it's more likely the membranes have ruptured.
Excerpted from Wikipedia’s “nitrazine” article, available under the CC BY-SA 4.0 licence.