nonunion
Sign in to saveAlso known as pseudoarthrosis, Fractures, Ununited
Nonunion is permanent failure of healing following a broken bone unless intervention (such as surgery) is performed. A fracture with nonunion generally forms a structural resemblance to a fibrous joint, and is therefore often called a "false joint" or pseudoarthrosis (from Greek pseudo-, meaning false, , meaning joint, and -osis, meaning abnormal condition). The diagnosis is generally made when there is no healing between two sets of medical imaging, such as X-ray or CT scan. This is generally after 6–8 months.
Research
22,554 papers- Fracture nonunion in long bones: A literature review of risk factors and surgical management.Injury · 2021
- Scaphoid Nonunion: A Review of Surgical Strategies.Orthopedics · 2022
- Nonunion.The Veterinary clinics of North America. Small animal practice · 1987
- Aseptic humeral shaft nonunion.Orthopaedics & traumatology, surgery & research : OTSR · 2023
- A unified theory of bone healing and nonunion: BHN theory.The bone & joint journal · 2016
via PubMed
Clinical Trials
74 registered- PHASE4TERMINATEDA Single Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing SurgeryDePuy International · NCT00872794
- UNKNOWNLong-term Surgical Outcomes of Scaphoid Proximal Pole Fracture NonunionTaipei Veterans General Hospital, Taiwan · NCT03701269
- PHASE4WITHDRAWNA Multi-centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Polyethylene-on-metal Bearing in Primary Total Hip ReplacementDePuy International · NCT00208429
- UNKNOWNComparative Study of Gene-activated Bone Substitute and Autobone in Treatment of Long Bone NonunionsHistograft Co., Ltd. · NCT04705857
- PHASE1UNKNOWNMesenchymal Stem Cells; Donor and Role in Management and Reconstruction of Nonunion FractureIndonesia University · NCT01626625
- NANOT_YET_RECRUITINGAllograft vs. Autograft NonunionWake Forest University Health Sciences · NCT07310082
Wikidata facts
Show 2 more facts
- Commons category
- Pseudarthrosis
- NCI Thesaurus ID
- C118392
via Wikidata · CC0
~8 min read
Article
15 sectionsContents
- Signs and symptoms
- Causes
- Risk factors
- Types of nonunion
- Hypertrophic nonunion
- Atrophic nonunion
- Oligotrophic nonunion
- Diagnosis
- Treatment
- Surgery
- Bone stimulation
- Prognosis
- See also
- References
- External links
Nonunion is permanent failure of healing following a broken bone unless intervention (such as surgery) is performed. A fracture with nonunion generally forms a structural resemblance to a fibrous joint, and is therefore often called a "false joint" or pseudoarthrosis (from Greek pseudo-, meaning false, , meaning joint, and -osis, meaning abnormal condition). The diagnosis is generally made when there is no healing between two sets of medical imaging, such as X-ray or CT scan. This is generally after 6–8 months.
Nonunion is a serious complication of a fracture and may occur when the fracture moves too much, has a poor blood supply or gets infected. Patients who smoke have a higher incidence of nonunion. The normal process of bone healing is interrupted or stalled.