ODC1

Name

ornithine decarboxylase 1

Type

protein-coding

Aliases

BABS, NEDBA, NEDBIA, ODC

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013].

via MyGene.info

Gene · Ensembl

ornithine decarboxylase 1

Symbol

ODC1

Biotype

Protein coding

Organism

Homo sapiens

Location

2:10,435,417-10,450,116

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein ODC1 PDB 1d7k.png

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