OSBPL1A
Sign in to saveAlso known as ORP-1, ORP1, OSBPL1B, oxysterol binding protein like 1A
Oxysterol-binding protein-related protein 1 is a protein that in humans is encoded by the OSBPL1A gene.
Gene data
OSBPL1A- Name
- oxysterol binding protein like 1A
- Type
- protein-coding
- Position
- 24,162,045–24,397,908 (−)
- Aliases
- ORP-1, ORP1, OSBPL1B
- Ensembl
- ENSG00000141447
- RefSeq RNA
- NM_001242508.1, NM_018030.4, NM_080597.4, NM_133268.1, XM_017025530.2
- RefSeq protein
- NP_001229437.1, NP_060500.3, NP_542164.2, XP_016881019.1, XP_047293243.1
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
oxysterol binding protein like 1A
- Symbol
- OSBPL1A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 18:24,162,045-24,397,908
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Oxysterol-binding protein-related protein 1 is a protein that in humans is encoded by the OSBPL1A gene.
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms.
Excerpted from Wikipedia’s “OSBPL1A” article, available under the CC BY-SA 4.0 licence.