osteosarcoma
Also known as Osteogenic sarcoma, Skeletal sarcoma, osteoid sarcoma, OSTEOSARCOMA, MALIGNANT, sarcoma of osteoid
An osteosarcoma (OS) or osteogenic sarcoma (OGS) is a cancerous tumor in a bone. Specifically, it is an aggressive malignant neoplasm that arises from primitive transformed cells of mesenchymal origin (and thus a sarcoma) and that exhibits osteoblastic differentiation and produces malignant osteoid.
Key facts
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- Intermediate-magnification micrograph of an osteosarcoma (center and right of image) adjacent to non-malignant bone (left-bottom of image): The top-right of the image has poorly differentiated tumor. Osteoid with a high density of malignant cells is seen between the non-malignant bone and poorly differentiated tumor (H&E stain).
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- Oncology
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- Osteosarcoma
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- Osteosarcoma - intermed mag.jpg
via Wikipedia infobox
Research
48,490 papers- Telangiectatic osteosarcoma.Archives of pathology & laboratory medicine · 2012
- Targeting WNT5B and WNT10B in osteosarcoma.Oncotarget · 2024
- Periosteal Osteosarcoma: Emerging Clinical Concepts, Evolving Treatment Options: A Narrative Review.Current pain and headache reports · 2025
- DNA cytometry of osteosarcoma.
Article
18 sectionsContents
- Signs and symptoms
- Causes
- Mechanism
- Diagnosis
- Variants
- Treatment
- Prognosis
- Epidemiology
- Other animals
- Risk factors
- Clinical presentation
- Treatment and prognosis
- Molecular alterations
- Cats
- Dinosaurs
- References
- Further reading
- External links
An osteosarcoma (OS) or osteogenic sarcoma (OGS) is a cancerous tumor in a bone. Specifically, it is an aggressive malignant neoplasm that arises from primitive transformed cells of mesenchymal origin (and thus a sarcoma) and that exhibits osteoblastic differentiation and produces malignant osteoid.
Osteosarcoma is the most common histological form of primary bone sarcoma. It is most prevalent in teenagers and young adults.