
oxalate compound
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Oxalate (systematic IUPAC name: ethanedioate) is an anion with the chemical formula . This dianion is colorless. It occurs naturally, including in some foods. It forms a variety of salts, for example sodium oxalate (), and several esters such as dimethyl oxalate (). It is a conjugate base of oxalic acid. At neutral pH in aqueous solution, oxalic acid converts completely to oxalate.
Research
4,594 papers- Oxalate disrupts monocyte and macrophage cellular function via Interleukin-10 and mitochondrial reactive oxygen species (ROS) signaling.Redox biology · 2023
- Diet-induced oxalate nephropathy.BMJ case reports · 2019
- Contribution of Dietary Oxalate and Oxalate Precursors to Urinary Oxalate Excretion.Nutrients · 2020
- The protective effect of caffeine against oxalate-induced epithelial-mesenchymal transition in renal tubular cells via mitochondrial preservation.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2024
- Baseline abundance of oxalate-degrading bacteria determines response to Oxalobacter formigenes probiotic therapy.Gut microbes · 2025
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Encyclopedic overview
11 sectionsContents
- Relationship to oxalic acid
- Structure
- Occurrence in nature
- Physiological effects
- As a ligand for metal ions
- Excess
- Acquired
- Congenital
- References
- Further reading
- External links
Oxalate (systematic IUPAC name: ethanedioate) is an anion with the chemical formula . This dianion is colorless. It occurs naturally, including in some foods. It forms a variety of salts, for example sodium oxalate (), and several esters such as dimethyl oxalate (). It is a conjugate base of oxalic acid. At neutral pH in aqueous solution, oxalic acid converts completely to oxalate.
==Relationship to oxalic acid== The dissociation of protons from oxalic acid proceeds in a determined order; as for other polyprotic acids, loss of a single proton results in the monovalent hydrogenoxalate anion . A salt with this anion is sometimes called an acid oxalate, monobasic oxalate, or hydrogen oxalate. The equilibrium constant (Ka) for loss of the first proton is (pKa = 1.27). The loss of the second proton, which yields the oxalate ion, has an equilibrium constant of (pKa = 4.28). These values imply, in solutions with neutral pH, no oxalic acid and only trace amounts of hydrogen oxalate exist. The literature is often unclear on the distinction between , , and , and the collection of species is referred to as oxalic acid.
Excerpted from Wikipedia’s “oxalate compound” article, available under the CC BY-SA 4.0 licence.