phenescaline
Sign in to saveAlso known as 3,5-dimethoxy-4-phenylethoxyphenethylamine
Phenescaline, also known as 3,5-dimethoxy-4-phenylethoxyphenethylamine, is a psychoactive drug of the phenethylamine and scaline families related to mescaline. It is the derivative of mescaline in which the methoxy group at the 4 position has been replaced with a phenylethoxy group. In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists phenescaline's dose as greater than 150mg orally and its duration as unknown. The effects of phenescaline have been reported to include threshold effects and a vague unreal feeling as if one had not had enough sleep. The drug shows
Wikidata facts
- Mass
- 301.16779359599997
Show 2 more facts
- canonical SMILES
- COc2cc(cc(OC)c2OCCc1ccccc1)CCN
- chemical formula
- C₁₈H₂₃NO₃
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Phenescaline, also known as 3,5-dimethoxy-4-phenylethoxyphenethylamine, is a psychoactive drug of the phenethylamine and scaline families related to mescaline. It is the derivative of mescaline in which the methoxy group at the 4 position has been replaced with a phenylethoxy group. In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists phenescaline's dose as greater than 150mg orally and its duration as unknown. The effects of phenescaline have been reported to include threshold effects and a vague unreal feeling as if one had not had enough sleep. The drug shows affinity for the serotonin 5-HT2A receptor (Ki = 59nM). The chemical synthesis of phenescaline has been described. Phenescaline was first described in the literature by Shulgin in PiHKAL in 1991.
== See also == Scaline 4-PhPr-3,5-DMA Benzscaline Phescaline