pheophorbide
Sign in to saveAlso known as phaeophorbide
Pheophorbide or phaeophorbide is a product of chlorophyll breakdown and a derivative of pheophytin where both the central magnesium has been removed and the phytol tail has been hydrolyzed. It is used as a photosensitizer in photodynamic therapy.
Research
824 papers- Pheophorbide a: State of the Art.Marine drugs · 2020
- Nanoparticles improved pheophorbide-a mediated photodynamic therapy for cancer.Lasers in medical science · 2025
- The chlorophyll catabolite pheophorbide a as a photosensitizer for the photodynamic therapy.Current medicinal chemistry · 2012
- Pheophorbide a May Regulate Jasmonate Signaling during Dark-Induced Senescence.Plant physiology · 2020
- Evaluating pheophorbide-a as a photosensitizer in oral cancer photodynamic therapy: A systematic review.Dental and medical problems · 2026
via PubMed
Wikidata facts
- Mass
- 592.26857
Show 3 more facts
- chemical formula
- C₃₅H₃₆N₄O₅
- canonical SMILES
- CCC1=C2C=C3C(=C4C(=O)C(C(=C5C(C(C(=N5)C=C6C(=C(C(=CC(=C1C)N2)N6)C=C)C)C)CCC(=O)O)C4=N3)C(=O)OC)C
- isomeric SMILES
- CCC1=C2C=C3C(=C4C(=O)[C@@H](C(=C5[C@H]([C@@H](C(=N5)C=C6C(=C(C(=CC(=C1C)N2)N6)C=C)C)C)CCC(=O)O)C4=N3)C(=O)OC)C
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Article
1 sectionsContents
- References
Pheophorbide or phaeophorbide is a product of chlorophyll breakdown and a derivative of pheophytin where both the central magnesium has been removed and the phytol tail has been hydrolyzed. It is used as a photosensitizer in photodynamic therapy.
Pheophorbide may be generated by digestion of ingested plant matter. Both worm (Caenorhabditis elegans) and mouse mitochondria are able to use the molecule in a form of ad hoc photoheterotrophy.