polyhydroxyethylmethacrylate
Sign in to saveAlso known as Polyhydroxyethyl Methacrylate, poly(2 hydroxyethyl methacrylate
Poly(2-hydroxyethyl methacrylate) (pHEMA) is a polymer that forms a hydrogel in water. It was invented by Drahoslav Lim and Otto Wichterle for biological use. Together they succeeded in preparing a cross-linking gel which absorbed up to 40% of water, exhibited suitable mechanical properties and was transparent. They patented this material in 1953.
Research
102 papers- Implementation of a Macroporous Polyhydroxyethylmethacrylate Cryogel-Based Mini-Bioreactor System to Improve Monoclonal Antibody Production.Frontiers in bioscience (Elite edition) · 2024
- Inverse opal pH sensors with various protic monomers copolymerized with polyhydroxyethylmethacrylate hydrogel.Analytica chimica acta · 2012
- Polyhydroxyethylmethacrylate-based magnetic DNA-affinity beads for anti-DNA antibody removal from systemic lupus erythematosus patient plasma.Journal of chromatography. B, Biomedical sciences and applications · 2001
- Effect of a synthetic dressing formed on a burn wound in rats: a comparison of allografts, collagen sheets, and polyhydroxyethylmethacrylate in the control of wound infection.Applied microbiology · 1974
- Uranium and thorium adsorption from aqueous solution using a novel polyhydroxyethylmethacrylate-pumice composite.Journal of environmental radioactivity · 2013
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Article
5 sectionsContents
- Synthesis
- Applications
- Contact lenses
- Cell culture
- References
Poly(2-hydroxyethyl methacrylate) (pHEMA) is a polymer that forms a hydrogel in water. It was invented by Drahoslav Lim and Otto Wichterle for biological use. Together they succeeded in preparing a cross-linking gel which absorbed up to 40% of water, exhibited suitable mechanical properties and was transparent. They patented this material in 1953.
==Synthesis== pHEMA hydrogel for intraocular lenses can be synthesized by solution polymerization using 2-hydroxyethyl methacrylate (HEMA) as raw material, ammonium persulfate and sodium pyrosulfite (APS/SMBS) as catalyst, and triethyleneglycol dimethacrylate (TEGDMA) as cross-linking additive.