RIMBP2
Sign in to saveAlso known as PPP1R133, RBP2, RIM-BP2, RIMS binding protein 2
RIMS binding protein 2 is a protein that in humans is encoded by the RIMBP2 gene. This protein plays a significant role in synaptic transmission and is involved in the regulation of voltage-gated calcium channels, which are crucial for neurotransmitter release at synapses.
Gene data
RIMBP2- Name
- RIMS binding protein 2
- Type
- protein-coding
- Aliases
- PPP1R133, RBP2, RIM-BP2
Predicted to be involved in neuromuscular synaptic transmission. Predicted to be located in plasma membrane and synapse. Predicted to be active in presynaptic active zone cytoplasmic component. [provided by Alliance of Genome Resources, Apr 2022]
via MyGene.info
Gene · Ensembl
RIMS binding protein 2
- Symbol
- RIMBP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:130,396,131-130,768,228
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 14672
- exact match
- identifiers.org/ncbigene/23504
- genomic end
- 130716281
- genomic start
- 130880682
- cytogenetic location
- 12q24.33
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function and characteristics
- Clinical relevance
- References
- External links
RIMS binding protein 2 is a protein that in humans is encoded by the RIMBP2 gene. This protein plays a significant role in synaptic transmission and is involved in the regulation of voltage-gated calcium channels, which are crucial for neurotransmitter release at synapses.
== Function and characteristics == RIMBP2 is primarily located in the presynaptic active zones of neurons, where it contributes to the organization and maintenance of synaptic structures. It is essential for the proper functioning of synaptic vesicles and calcium-dependent processes that facilitate communication between neurons.