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solubility

thumb|Example of a dissolved solid (left) thumb|upright|Formation of crystals in a 4.2 Molar concentration|M [[ammonium sulfate solution. The solution was initially prepared at 20 °C and then stored for 2 days at 4 °C.]]

AI overview

Solubility is the ability of a substance to dissolve into another substance, like salt dissolving in water, and it can change depending on conditions like temperature. It matters because understanding how much of a substance can dissolve helps predict when crystals will form or when solutions will become saturated.

AI-generated from the Wikipedia summary — may contain errors.

Research

442,967 papers

Estimating drug solubility in the gastrointestinal tract.ReviewAdvanced drug delivery reviews · 2007Dressman JB, Vertzoni M, Goumas K et al.DOI: 10.1016/j.addr.2007.05.009
Polyphenol-solubility alters amyloid fibril formation of α-synuclein.Protein science : a publication of the Protein Society · 2021So M, Kimura Y, Yamaguchi K et al.DOI: 10.1002/pro.4130
Solubility of Pharmaceutical Ingredients in Natural Edible Oils.Molecular pharmaceutics · 2020Brinkmann J, Rest F, Luebbert C et al.DOI: 10.1021/acs.molpharmaceut.0c00215
Solubility and thermodynamic analysis of famotidine polymorphs in pure solvents.International journal of pharmaceutics · 2021Soto R, Svärd MDOI: 10.1016/j.ijpharm.2021.121031
A review of drug solubility in human intestinal fluids: implications for the prediction of oral absorption.ReviewEuropean journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2014Augustijns P, Wuyts B, Hens B et al.DOI: 10.1016/j.ejps.2013.08.027
Solubility of pharmaceutical ingredients in triglycerides.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2019Brinkmann J, Huxoll F, Luebbert C et al.DOI: 10.1016/j.ejpb.2019.10.012
Solubility and Thermodynamic Investigation of Meta-Autunite Group Uranyl Arsenate Solids with Monovalent Cations Na and K.Environmental science & technology · 2023Meza I, Gonzalez-Estrella J, Burns PC et al.DOI: 10.1021/acs.est.2c06648
Solubility measurement and thermodynamic modeling of pantoprazole sodium sesquihydrate in supercritical carbon dioxide.Scientific reports · 2022Sodeifian G, Garlapati C, Razmimanesh F et al.DOI: 10.1038/s41598-022-11887-1

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Wikidata facts

Image: SolubilityVsTemperature.png

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Commons category: Solubility

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~31 min read

Article

27 sections

Contents

Quantification of solubility
Per quantity of solvent
Per quantity of solution
Liquid and gaseous solutes
Conversion of solubility values
Qualifiers used to describe extent of solubility
Molecular view
Factors affecting solubility
Temperature
Pressure
Solubility of gases
Polarity
Rate of dissolution
Theories of solubility
Solubility product
Other theories
Applications
Differential solubility
Solubility of ionic compounds in water
Solubility of organic compounds
Solid solution
Incongruent dissolution
Solubility prediction
See also
Notes
References
External links

In chemistry, solubility is the ability of a substance, the solute, to form a solution with another substance, the solvent. Insolubility is the opposite property, the inability of the solute to form such a solution.