SYCP3
Sign in to saveAlso known as COR1, SCP3, SPGF4, RPRGL4, synaptonemal complex protein 3
Synaptonemal complex protein 3 is a protein that in humans is encoded by the SYCP3 gene. It is a component of the synaptonemal complex formed between homologous chromosomes during the prophase of meiosis.
Gene data
SYCP3- Name
- synaptonemal complex protein 3
- Type
- protein-coding
- Position
- 101,728,646–101,739,534 (−)
- Aliases
- COR1, RPRGL4, SCP3, SPGF4
- Ensembl
- ENSG00000139351
- RefSeq RNA
- NM_001177948.2, NM_001177949.2, NM_153694.5, XM_005268922.6, XM_005268924.2
- RefSeq protein
- NP_001171419.1, NP_001171420.1, NP_710161.1, XP_005268979.4, XP_005268981.1
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
synaptonemal complex protein 3
- Symbol
- SYCP3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:101,728,646-101,739,534
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Gene family
- References
- Further reading
- External links
Synaptonemal complex protein 3 is a protein that in humans is encoded by the SYCP3 gene. It is a component of the synaptonemal complex formed between homologous chromosomes during the prophase of meiosis.
== Gene family == {|style="float:left; margin-right: 0.5em" | |} SYCP3 is also known as COR1. It contains a conserved coiled-coil domain that is also found in the FAM9 (FAM9A, FAM9B) family of proteins, found on the human X chromosome.
Excerpted from Wikipedia’s “SYCP3” article, available under the CC BY-SA 4.0 licence.