Structure via PubChem · Public domain (PubChem)
thiacetarsamide
Sign in to saveAlso known as arsenamide
Arsenamide or thiacetarsamide (trade name Caparsolate) is an arsenical. It is a proposed chemotherapeutic agent against canine filaria and trichomonas.
Chemical data
- Formula
- C11H12AsNO5S2
- Molecular weight
- 377.3 g/mol
- IUPAC name
- 2-[(4-carbamoylphenyl)-(carboxymethylsulfanyl)arsanyl]sulfanylacetic acid
- SMILES
- C1=CC(=CC=C1C(=O)N)[As](SCC(=O)O)SCC(=O)O
- InChIKey
- YBQWEUNEYYXYOI-UHFFFAOYSA-N
- Polar surface area
- 168 Ų
- H-bond donors
- 3
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Research
91 papers- Thiacetarsamide (adulticide) versus melarsomine (RM 340) developed as macrofilaricide (adulticide and larvicide) to cure canine heartworm infection in dogs.Annales de recherches veterinaires. Annals of veterinary research · 1992
- Feline dirofilariasis.The Veterinary clinics of North America. Small animal practice · 1984
- Thiacetarsamide treatment of heartworm infection in dogs.Seminars in veterinary medicine and surgery (small animal) · 1987
- Thiacetarsamide in dogs with Dirofilaria immitis: influence of decreased liver function on drug efficacy.American journal of veterinary research · 1986
- Complications following thiacetarsamide sodium therapy in Louisiana dogs with naturally-occurring heartworm disease.The Cornell veterinarian · 1985
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 376.937
Show 3 more facts
- chemical formula
- C₁₁H₁₂AsNO₅S₂
- canonical SMILES
- C1=CC(=CC=C1C(=O)N)[As](SCC(=O)O)SCC(=O)O
- Commons category
- Arsenamide
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
{{chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 443400454 | ImageFile = Arsenamide.png | ImageClass = skin-invert-image | ImageSize = 210px | ImageFile1 = | ImageSize1 = 230 | ImageAlt1 = Space-filling model of arsenamide | PIN=2,2′-{[(4-Carbamoylphenyl)arsanediyl]bis(sulfanediyl)}diacetic acid | OtherNames=Thiacetarsamide |Section1= |Section2= |Section3= }}
Arsenamide or thiacetarsamide (trade name Caparsolate) is an arsenical. It is a proposed chemotherapeutic agent against canine filaria and trichomonas.
Excerpted from Wikipedia’s “thiacetarsamide” article, available under the CC BY-SA 4.0 licence.