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thiol
Sign in to saveAlso known as mercaptan, Sulfhydryl Compounds, Sulfhydryl Compound
thumb|upright=0.5|right|Thiol with a sulfhydryl group.
A thiol is a type of organic compound that contains a sulfur atom bonded to a hydrogen atom, giving it unique chemical properties. Thiols are important in biological systems and industrial chemistry because this sulfur-hydrogen group makes them reactive and useful for various chemical processes and functions in living organisms.
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Research
146,447 papers- Thiol-disulfide homeostasis: an integrated approach with biochemical and clinical aspects.Turkish journal of medical sciences · 2020
- Thiol-based antioxidants.Current topics in cellular regulation · 2000
- Fluorescent Probes for Live Cell Thiol Detection.Molecules (Basel, Switzerland) · 2021
- Thiol reactive probes and chemosensors.Sensors (Basel, Switzerland) · 2012
- The clinical potential of thiol redox proteomics.Expert review of proteomics · 2020
via PubMed
Wikidata facts
Show 3 more facts
- Commons category
- Thiols
- canonical SMILES
- S[*]
- CXSMILES
- S[*] |$;R$|
via Wikidata · CC0
~17 min read
Article
28 sectionsContents
- Nomenclature
- Physical properties
- Odor
- Boiling points and solubility
- Structure and bonding
- Characterization
- Preparation
- Laboratory methods
- Classes of thiols
- Alkyl and aryl thiols
- Dithiols
- Unsaturated thiols
- Thioalcohols
- Thiol-carboxylic acids
- Aminothiols
- Reactions
- Acidity
- ''S''-Based nucleophilicity
- Redox
- Metal ion complexation
- Thiyl radicals
- Biological importance
- Cysteine and cystine
- Cofactors
- Drugs
- See also
- References
- External links
thumb|upright=0.5|right|Thiol with a sulfhydryl group.
In organic chemistry, a thiol (; ), or thiol derivative, is any organosulfur compound of the form , where R represents an alkyl or other organic substituent. The functional group itself is referred to as either a thiol group or a sulfhydryl group, or a sulfanyl group. Thiols are the sulfur analogue of alcohols (that is, sulfur takes the place of oxygen in the hydroxyl () group of an alcohol), and the word is a blend of "thio-" with "alcohol".