Structure via PubChem · Public domain (PubChem)
Thioproscaline
Sign in to saveThioproscaline (TP), or 4-thioproscaline (4-TP), also known as 3,5-dimethoxy-4-propylthiophenethylamine, is a psychedelic drug of the phenethylamine and scaline families related to mescaline. It is the analogue of proscaline in which the propoxy group at the 4 position has been replaced with a propylthio group.
Chemical data
- Formula
- C13H21NO2S
- Molecular weight
- 255.38 g/mol
- IUPAC name
- 2-(3,5-dimethoxy-4-propylsulfanylphenyl)ethanamine
- SMILES
- CCCSC1=C(C=C(C=C1OC)CCN)OC
- InChIKey
- BQFDSMXQCJFKCH-UHFFFAOYSA-N
- XLogP
- 2.7
- Polar surface area
- 69.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 255.129299912
Show 2 more facts
- canonical SMILES
- COc1cc(cc(OC)c1SCCC)CCN
- chemical formula
- C₁₃H₂₁NO₂S
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- External links
Thioproscaline (TP), or 4-thioproscaline (4-TP), also known as 3,5-dimethoxy-4-propylthiophenethylamine, is a psychedelic drug of the phenethylamine and scaline families related to mescaline. It is the analogue of proscaline in which the propoxy group at the 4 position has been replaced with a propylthio group.
In his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, Alexander Shulgin lists thioproscaline's dose as 20 to 25mg orally and its duration as 10 to 15hours. Its onset is more than 2hours. The drug has approximately 10 to 16times the potency of mescaline. The effects of thioproscaline have been reported to include extremely rich closed-eye imagery, quite a bit of open-eye visuals, body load, body heaviness, heavy pressure at the back of the neck, feeling vulnerable, dizziness, and hyperreflexia. It was remarked that the psychoactive effects did not seem worth the physical side effects, although it was suggested that lower doses might be better.
Excerpted from Wikipedia’s “Thioproscaline” article, available under the CC BY-SA 4.0 licence.