tilorone
Sign in to saveTilorone (trade names Amixin, Lavomax and others) is the first recognized synthetic, small molecular weight compound that is an orally active interferon inducer. It is used as an antiviral drug in some countries which do not require double-blind placebo-controlled studies, including Russia. It is effective against Ebola virus in mice. It shows activity against Eastern equine encephalitis and related viruses.
Research
482 papers- Tilorone hydrochloride: the drug profile.Topics in current chemistry · 1977
- Tilorone attenuates high-fat diet-induced hepatic steatosis by enhancing BMP9-Smad1/5/8 signaling.GeroScience · 2026
- Tilorone, a Broad-Spectrum Antiviral for Emerging Viruses.Antimicrobial agents and chemotherapy · 2020
- Tilorone mitigates the propagation of α-synucleinopathy in a midbrain-like organoid model.Journal of translational medicine · 2024
- Tilorone and related bis-basic substituted polycyclic aromatic and heteroaromatic compounds.Progress in medicinal chemistry · 1981
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Wikidata facts
- Mass
- 410.257
Show 3 more facts
- canonical SMILES
- CCN(CC)CCOC1=CC2=C(C=C1)C3=C(C2=O)C=C(C=C3)OCCN(CC)CC
- chemical formula
- C₂₅H₃₄N₂O₃
- Commons category
- Tilorone
Sources (2)
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Article
3 sectionsContents
- Pharmacology
- See also
- References
Tilorone (trade names Amixin, Lavomax and others) is the first recognized synthetic, small molecular weight compound that is an orally active interferon inducer. It is used as an antiviral drug in some countries which do not require double-blind placebo-controlled studies, including Russia. It is effective against Ebola virus in mice. It shows activity against Eastern equine encephalitis and related viruses.
==Pharmacology== Tilorone activates the production of interferon.