tipiracil
Sign in to saveAlso known as MA-1, TAS-1-462
Tipiracil is a drug used in the treatment of cancer. It is approved for use in form of the combination drug trifluridine/tipiracil for the treatment of unresectable advanced or recurrent colorectal cancer.
Wikidata facts
- Mass
- 242.057053
Show 4 more facts
- chemical formula
- C₉H₁₁ClN₄O₂
- World Health Organisation international non-proprietary name
- tipiracil
- canonical SMILES
- C1CC(=N)N(C1)CC2=C(C(=O)NC(=O)N2)Cl
- Commons category
- Tipiracil
via Wikidata · CC0
~3 min read
Article
8 sectionsContents
- Adverse effects
- Interactions
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Chemistry
- COVID-19
- References
Tipiracil is a drug used in the treatment of cancer. It is approved for use in form of the combination drug trifluridine/tipiracil for the treatment of unresectable advanced or recurrent colorectal cancer.
Tipiracil helps maintain the blood concentration of trifluridine by inhibiting the enzyme thymidine phosphorylase which metabolizes trifluridine.
Connections
ethanol
Entity
SARS-CoV-2
Entity
digital object identifier
Entity
chemical formula
Entity
hydrochloric acid
Entity
blood plasma
Entity
crystallography
Entity
methanol
Entity
molar mass
Entity
acetone
Entity
Colorectal cancer
Concept
hydrolysis
Entity
Q180686
Entity
diethyl ether
Entity
excretion
Entity
CAS Registry Number
Entity
Q229883
Entity
isopropyl alcohol
Entity
PubChem
Entity
pharmacokinetics
Entity