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Transversion
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Transversion

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thumb|right|300px|Illustration of a transversion: each of the 8 nucleotide changes between a purine and a pyrimidine (in red). The 4 other changes are Transition (genetics)|transitions (in blue).

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Transversion
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8 sections
Contents
  • Ratio of transitions to transversions
  • Spontaneous germline transversion
  • Consequences of transversion mutations
  • Transversions due to products of oxidative guanine damage
  • Transversion and p53 mutations in smoking-associated cancers
  • See also
  • References
  • External links

thumb|right|300px|Illustration of a transversion: each of the 8 nucleotide changes between a purine and a pyrimidine (in red). The 4 other changes are Transition (genetics)|transitions (in blue).

Transversion, in molecular biology, refers to a point mutation in DNA in which a single (two ring) purine (A or G) is changed for a (one ring) pyrimidine (T or C), or vice versa. A transversion can be spontaneous, or it can be caused by ionizing radiation or alkylating agents. It can only be reversed by a spontaneous reversion.

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