troxipide
Sign in to saveAlso known as 3,4,5-Trimethoxy-N-(3-piperidyl)benzamide
Troxipide is a drug used in the treatment of gastroesophageal reflux disease. Troxipide is a systemic non-antisecretory gastric cytoprotective agent with anti-ulcer, anti-inflammatory and mucus secreting properties irrespective of pH of stomach or duodenum. Troxipide is currently marketed in Japan (Aplace), China (Shuqi), South Korea (Defensa), and India (Troxip). It is used for the management of gastric ulcers, and amelioration of gastric mucosal lesions in acute gastritis and acute exacerbation of chronic gastritis.
Wikidata facts
- Mass
- 294.158
Show 2 more facts
- chemical formula
- C₁₅H₂₂N₂O₄
- canonical SMILES
- COC1=CC(=CC(=C1OC)OC)C(=O)NC2CCCNC2
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~9 min read
Article
11 sectionsContents
- Mechanism of action
- Gastric mucosal protection
- Stimulation of cytoprotective prostaglandins
- Suppression of gastric inflammation
- Enhancement of mucosal metabolism
- Stimulation of mucosal microcirculation
- Anti-''Helicobacter pylori'' action
- Pharmacokinetics
- Clinical experience
- Safety and tolerability
- References
Troxipide is a drug used in the treatment of gastroesophageal reflux disease. Troxipide is a systemic non-antisecretory gastric cytoprotective agent with anti-ulcer, anti-inflammatory and mucus secreting properties irrespective of pH of stomach or duodenum. Troxipide is currently marketed in Japan (Aplace), China (Shuqi), South Korea (Defensa), and India (Troxip). It is used for the management of gastric ulcers, and amelioration of gastric mucosal lesions in acute gastritis and acute exacerbation of chronic gastritis.
== Mechanism of action ==