United States at the 2016 Summer Olympics

The United States of America (USA), represented by the United States Olympic Committee (USOC), competed at the 2016 Summer Olympics in Rio de Janeiro, from August 5 to 21, 2016. U.S. athletes have appeared in every Summer Olympic Games of the modern era, with the exception of the 1980 Summer Olympics in Moscow, which they boycotted in protest of the Soviet invasion of Afghanistan. For the second consecutive time in the Summer Olympics, the United States was represented by more female than male athletes (264 men and 291 women).

The 2016 Olympics were the third most successful for the United States in terms of overall medal count (121) and the most successful not held in the United States: U.S. athletes won 231 total medals at St. Louis in 1904 and 174 at Los Angeles in 1984. These Games also witnessed the thousandth Summer Olympic gold medal for the Americans.