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vaccine
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A vaccine is a biological preparation that provides active acquired immunity to a particular infectious or malignant disease. The safety and effectiveness of vaccines has been widely studied and verified. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the immune system to recognize the agent as a threat, destroy it, and recognize further and destroy any of the microorganisms associated with that agent that it may encounter in the
A vaccine is a biological preparation containing a weakened or killed disease-causing microorganism (or its components) that trains your immune system to recognize and fight that specific disease. Vaccines matter because they provide protection against infectious and malignant diseases, and their safety and effectiveness have been widely studied and verified.
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Key facts
- Medical intervention (new).name
- Vaccine
- Medical intervention (new).image
- Smallpox vaccine.jpg
- Medical intervention (new).caption
- Smallpox vaccine and equipment for administering it
- Medical intervention (new).MeshID
- D014612
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Research
593,686 papers- Addressing HPV vaccine myths: practical information for healthcare providers.ReviewHuman vaccines & immunotherapeutics · 2019Bednarczyk RADOI: 10.1080/21645515.2019.1565267
- Vaccine hesitancy and healthcare providers.ReviewVaccine · 2016Paterson P, Meurice F, Stanberry LR et al.DOI: 10.1016/j.vaccine.2016.10.042
- A systematic review of factors affecting vaccine uptake in young children.Vaccine · 2017Smith LE, Amlôt R, Weinman J et al.DOI: 10.1016/j.vaccine.2017.09.046
- [Vaccine-associated adverse events in cats].ReviewTierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere · 2025Weidinger AK, Hartmann K, Bergmann MDOI: 10.1055/a-2514-1323
- Vaccine Hesitancy in Japan: From a Perspective on Medical Uncertainty and Trans-Scientific Theory.ReviewF1000Research · 2022Hosoda MDOI: 10.12688/f1000research.125159.2
- Vaccine-preventable diseases in Europe: where do we stand?ReviewExpert review of vaccines · 2014Wicker S, Maltezou HCDOI: 10.1586/14760584.2014.933077
- The HPV vaccine mandate controversy.ReviewJournal of pediatric and adolescent gynecology · 2007Haber G, Malow RM, Zimet GDDOI: 10.1016/j.jpag.2007.03.101
- Dismissal policies for vaccine refusal among US physicians: a literature review.ReviewHuman vaccines & immunotherapeutics · 2020Garcia TB, O'Leary STDOI: 10.1080/21645515.2020.1724742
via PubMed
Wikidata facts
- Image
- Smallpox vaccine.jpg
Show 4 more facts
- hashtag
- vaccines
- Commons category
- Vaccines
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- NCI Thesaurus ID
- C923
Sources (7)
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~53 min read
Article
48 sectionsContents
- Effectiveness
- Limitations
- Safety
- Types
- Attenuated
- Inactivated
- Toxoid
- Subunit
- Conjugate
- Outer membrane vesicle
- Heterotypic
- Genetic vaccine
- Viral vector
- RNA
- DNA
- Experimental
- Valence
- Interactions
- Other contents
- Adjuvants
- Preservatives
- Excipients
- Nomenclature
- Licensing
- World Health Organization
- European Union
- United States
- India
- Postmarketing surveillance
- Scheduling
- Economics of development
- Patents
- Production
- Vaccine manufacturers
- Delivery systems
- Oral vaccines
- Microneedle vaccines
- Dermal patch vaccines
- In veterinary medicine
- DIVA vaccines
- History
- Generations of vaccines
- Trends
- Plants as bioreactors for vaccine production
- Vaccine hesitancy
- References
- Further reading
- External links
A vaccine is a biological preparation that provides active acquired immunity to a particular infectious or malignant disease. The safety and effectiveness of vaccines has been widely studied and verified. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the immune system to recognize the agent as a threat, destroy it, and recognize further and destroy any of the microorganisms associated with that agent that it may encounter in the future.
Vaccines can be prophylactic (to prevent or alleviate the effects of a future infection by a natural or "wild" pathogen), or therapeutic (to fight a disease that has already occurred, such as cancer). Some vaccines offer full sterilizing immunity, in which infection is prevented.
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