Structure via PubChem · Public domain (PubChem)
1,5-i-aedans
Sign in to saveAlso known as N-iodoacetyl-N'-(5-sulfonic-1-napthyl)ethylene-diamine, I-AED, IAEDANS, N-iodoacetyl-N'-(5-sulfo-1-naphthyl)ethylenediamine, N-(Iodoacetylaminoethyl)-5-naphthylamine-1-sulfonic acid
IAEDANS is an organic fluorophore (fluorescent molecule). It stands for 5-({2-[(iodoacetyl)amino]ethyl}amino)naphthalene-1-sulfonic acid. It is widely used as a marker in fluorescence spectroscopy.
In the Vinony graph
Within Vinony's link graph, 1,5-i-aedans is referenced by 2 other articles, and connects out to molecule, digital object identifier and chemical formula.
It is catalogued under topics including Chembox image size set, ECHA InfoCard ID from Wikidata and Fluorescent dyes.
Its subject is documented across 7 Wikipedia language editions.
Chemical data
- Formula
- C14H15IN2O4S
- Molecular weight
- 434.25 g/mol
- IUPAC name
- 5-[2-[(2-iodoacetyl)amino]ethylamino]naphthalene-1-sulfonic acid
- SMILES
- C1=CC2=C(C=CC=C2S(=O)(=O)O)C(=C1)NCCNC(=O)CI
- InChIKey
- ZMERMCRYYFRELX-UHFFFAOYSA-N
- XLogP
- 1.9
- Polar surface area
- 104 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Research
267 papers- Inactivation of firefly luciferase with N-(iodoacetyl)-N'- (5-sulfo-1-naphthyl)ethylenediamine (I-AEDANS).Archives of biochemistry and biophysics · 1997
- Affinity labeling of phosphoenolpyruvate carboxykinase with 1, 5-I-AEDANS.Biochemical and biophysical research communications · 1979
- Fluorescence-based peptide labeling and fractionation strategies for analysis of cysteine-containing peptides.Analytical chemistry · 2005
- N-Iodoacetyl-N'-(5-sulfo-1-naphthyl)ethylenediamine modification of myosin from chicken gizzard.Journal of biochemistry · 1985
- Probe studies of the MgADP state of muscle cross-bridges: microscopic and wavelength-dependent fluorescence polarization from 1,5-IAEDANS-labeled myosin subfragment 1 decorating muscle fibers.Biochemistry · 1987
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 433.979726
Show 3 more facts
- chemical formula
- C₁₄H₁₅IN₂O₄S
- canonical SMILES
- C1=CC2=C(C=CC=C2S(=O)(=O)O)C(=C1)NCCNC(=O)CI
- subject has role
- fluorophore
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
{{Chembox | verifiedrevid = 443867178 | ImageFile=5-((2-(2-iodoacetamido)ethyl)amino)naphthalene-1-sulfonic_acid_200.svg | ImageSize=200px | PIN=5-{[2-(2-Iodoacetamido)ethyl]amino}naphthalene-1-sulfonic acid | OtherNames=5-[2-[(2-Iodo-1-oxoethyl)amino]ethylamino]-1-naphthalenesulfonic acid1,5-IAEDANS |Section1= |Section2= |Section3= }}
IAEDANS is an organic fluorophore (fluorescent molecule). It stands for 5-({2-[(iodoacetyl)amino]ethyl}amino)naphthalene-1-sulfonic acid. It is widely used as a marker in fluorescence spectroscopy.
Excerpted from Wikipedia’s “1,5-i-aedans” article, available under the CC BY-SA 4.0 licence.