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EntityQ4596749· pop 14· linked from 8 articles

2,2-dimethoxypropane

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2,2-Dimethoxypropane (DMP) is an organic compound with the formula (CH3)2C(OCH3)2. A colorless liquid, it is the product of the condensation of acetone and methanol. DMP is used as a water scavenger in water-sensitive reactions. Upon acid-catalyzed reaction, DMP reacts quantitatively with water to form acetone and methanol. This property can be used to accurately determine the amount of water in a sample, alternatively to the Karl Fischer method.

Wikidata facts

Mass
104.084
Show 4 more facts
Commons category
2,2-Dimethoxypropane
melting point
-47.0
canonical SMILES
CC(C)(OC)OC
chemical formula
C₅H₁₂O₂
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2,2-Dimethoxypropane (DMP) is an organic compound with the formula (CH3)2C(OCH3)2. A colorless liquid, it is the product of the condensation of acetone and methanol. DMP is used as a water scavenger in water-sensitive reactions. Upon acid-catalyzed reaction, DMP reacts quantitatively with water to form acetone and methanol. This property can be used to accurately determine the amount of water in a sample, alternatively to the Karl Fischer method.

DMP is used to prepare acetonides from diols, where it is both a synthon for acetone and a scavenger for the water byproduct:

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