Structure via PubChem · Public domain (PubChem)
gepotidacin
Sign in to saveGepotidacin, sold under the brand name Blujepa, is an antibiotic medication used for the treatment of urinary tract infection or uncomplicated urogenital gonorrhea. Gepotidacin is a triazaacenaphthylene bacterial type II topoisomerase inhibitor. It is used as the salt gepotidacin mesylate, and is taken by mouth.
Chemical data
- Formula
- C24H28N6O3
- Molecular weight
- 448.5 g/mol
- IUPAC name
- (3R)-3-[[4-(3,4-dihydro-2H-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.04,12]dodeca-6,8(12),9-triene-5,11-dione
- SMILES
- C1CC2=CC(=NC=C2OC1)CNC3CCN(CC3)C[C@@H]4CN5C(=O)C=CC6=C5N4C(=O)C=N6
- InChIKey
- PZFAZQUREQIODZ-LJQANCHMSA-N
- XLogP
- 0.1
- Polar surface area
- 90.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- infection, gonorrhea, urinary tract infection, respiratory tract infectious disorder
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 448.222
Show 3 more facts
- chemical formula
- C₂₄H₂₈N₆O₃
- canonical SMILES
- C1CC2=CC(=NC=C2OC1)CNC3CCN(CC3)CC4CN5C(=O)C=CC6=C5N4C(=O)C=N6
- isomeric SMILES
- C1CC2=CC(=NC=C2OC1)CNC3CCN(CC3)C[C@@H]4CN5C(=O)C=CC6=C5N4C(=O)C=N6
Sources (2)
via Wikidata · CC0
~8 min read
Encyclopedic overview
12 sectionsContents
- Medical uses
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Synthesis
- Society and culture
- Legal status
- Names
- Research
- References
- Further reading
- External links
{{Infobox drug | image = Gepotidacin.svg | image_class = skin-invert-image | width = | alt = | caption =
| pronounce = | tradename = Blujepa | Drugs.com = | MedlinePlus = a625059 | DailyMedID = Gepotidacin | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = By mouth | class = | ATC_prefix = J01 | ATC_suffix = XX13 | ATC_supplemental = | biosimilars =
Excerpted from Wikipedia’s “gepotidacin” article, available under the CC BY-SA 4.0 licence.