telavancin
Sign in to saveAlso known as TD-6424, N(3'')-[2-(decylamino)ethyl]-29-{[(phosphonomethyl)amino]methyl}vancomycin, Telavancina, Télavancine, Telavancinum
Telavancin (trade name Vibativ by Cumberland Pharmaceuticals) is a bactericidal lipoglycopeptide for use in MRSA or other Gram-positive infections. Telavancin is a semi-synthetic derivative of vancomycin.
Research
473 papers- Telavancin.2006
- Telavancin: a novel lipoglycopeptide.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2009
- Telavancin: a novel lipoglycopeptide antimicrobial agent.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2007
- Telavancin: a novel semisynthetic lipoglycopeptide agent to counter the challenge of resistant Gram-positive pathogens.Therapeutic advances in infectious disease · 2017
- Telavancin (Theravance).Current opinion in investigational drugs (London, England : 2000) · 2005
via PubMed
Wikidata facts
- Mass
- 1753.637
- Has use
- medication
Show 6 more facts
- World Health Organisation international non-proprietary name
- telavancin
- canonical SMILES
- CCCCCCCCCCNCCNC1(CC(OC(C1O)C)OC2C(C(C(OC2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)C(C(C(=O)NC(C(=O)NC5C(=O)NC7C8=CC(=C(C=C8)O)C9=C(C(=C(C=C9C(NC(=O)C(C(C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)O)CNCP(=O)(O)O)O)CC(=O)N)NC(=O)C(CC(C)C)NC)O)Cl)CO)O)O)C
- chemical formula
- C₈₀H₁₀₆Cl₂N₁₁O₂₇P
- isomeric SMILES
- CCCCCCCCCCNCCN[C@]1(C[C@@H](O[C@H]([C@H]1O)C)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)[C@H]([C@H](C(=O)N[C@H](C(=O)N[C@H]5C(=O)N[C@@H]7C8=CC(=C(C=C8)O)C9=C(C(=C(C=C9[C@H](NC(=O)[C@H]([C@@H](C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)O)CNCP(=O)(O)O)O)CC(=O)N)NC(=O)[C@@H](CC(C)C)NC)O)Cl)CO)O)O)C
- subject has role
- bactericide
- medical condition treated
- bacterial pneumonia
via Wikidata · CC0
~2 min read
Encyclopedic overview
5 sectionsContents
- History
- Mechanism of action
- Adverse effects
- Interactions
- References
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 477861289 | image = Telavancin.svg | image_class = skin-invert-image | width = 200px | IUPAC_name = (1S,2R,18R,19R,22S,25R,28R,40S)-22-(2-Amino-2-oxoethyl)-5,15-dichloro-48-{[2-O-(3-{[2-(decylamino)ethyl]amino}-2,3,6-trideoxy-3-methyl-α-L-lyxo-hexopyranosyl)-β-D-glucopyranosyl]oxy}-2,18,32,35,37-pentahydroxy-19-[(N-methyl-D-leucyl)amino]-20,23,26,42,44-pentaoxo-36-{[(phosphonomethyl)amino]methyl}-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.23,6.214,17.18,12.129,33.010,25.034,39]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid
| tradename = Vibativ | Drugs.com = | MedlinePlus = a610004 | licence_US = Telavancin | pregnancy_AU = | pregnancy_US = C | licence_EU = yes | legal_AU = | legal_CA = | legal_UK = | legal_US = Rx-only | routes_of_administration = intravenous
Excerpted from Wikipedia’s “telavancin” article, available under the CC BY-SA 4.0 licence.