ACAD8

Also known as ACAD-8, ARC42, acyl-CoA dehydrogenase family member 8, IBDH

Isobutyryl-CoA dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the ACAD8 gene on chromosome 11.

Gene data

ACAD8

Name: acyl-CoA dehydrogenase family member 8
Type: protein-coding
Aliases: ACAD-8, ARC42, IBDH

This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency.[provided by RefSeq, Nov 2009].

via MyGene.info

Gene · Ensembl

acyl-CoA dehydrogenase family member 8

Symbol: ACAD8
Biotype: Protein coding
Organism: Homo sapiens
Location: 11:134,253,510-134,267,494
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein ACAD8 PDB 1rx0.png

Show 6 more facts

HomoloGene ID: 8662
exact match: identifiers.org/ncbigene/27034
genomic start: 134253548
genomic end: 134135749
cytogenetic location: 11q25
Commons category: Isobutyryl-CoA dehydrogenase

Sources (6)

via Wikidata · CC0

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Article

6 sections

Contents

Structure
Clinical significance
Function
References
External links
Further reading

Isobutyryl-CoA dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the ACAD8 gene on chromosome 11.

The protein encoded by ACAD8 is a mitochondrial protein belongs to the acyl-CoA dehydrogenase family of enzymes, which function to catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branched-chain amino acids. ACAD8 functions in catabolism of the branched-chain amino acid valine.