Adderall
Sign in to saveAlso known as Adderall XR, Attent
Adderall is the brand name of a fixed-dose combination medication used for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is also used as an athletic performance enhancer, cognitive enhancer, appetite suppressant, and recreationally as a euphoriant. Such uses are illegal in many countries. It is a central nervous system (CNS) stimulant of the phenethylamine class. It contains the amphetamines dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate. It is taken by mouth.
Key facts
- Drug.drug_name
- Amphetamine/dextroamphetaminesalt mixture (1:1)
- Drug.type
- combo
- Drug.image
- Amfetamin.svg
- Drug.image_class
- skin-invert-image
- Drug.alt
- an image of the amphetamine skeletal formula
- Drug.alt2
- a 2d image of the dextroamphetamine compound found in Adderall
- Drug.imageL
- Amphetamine (S-Isomer).png
- Drug.image_classL
- bg-transparent
- Drug.widthL
- 160
- Drug.imageR
- Amphetamine (R-Isomer) 3D-Ball-and-Stick.png
- Drug.image_classR
- bg-transparent
- Drug.widthR
- 160
- Drug.caption2
- Top: racemic amphetamine skeleton Bottom: (D)-amphetamine ball-and-stick model
- Drug.component1
- Amphetamine aspartate monohydrate
- Drug.class1
- 25% – stimulant()
- Drug.component2
- Amphetamine sulfate
- Drug.class2
- 25% – stimulant()
- Drug.component3
- Dextroamphetamine saccharate
via Wikipedia infobox
Clinical Trials
21 registered- PHASE2TERMINATEDAdderall XR Compared With Concerta in Treating Young Cancer Patients With Memory, Attention, and DepressionUniversity of South Florida · NCT00069927
- PHASE2COMPLETEDA Placebo-Controlled Study of Mixed Amphetamine Salts and Topiramate for the Treatment of Cocaine DependenceNew York State Psychiatric Institute · NCT00421603
- COMPLETEDA Study on Suicidality, Psychosis or Substance Abuse With Methylphenidate, Atomoxetine, Amphetamine/Dextroamphetamine or LisdexamfetamineJanssen Research & Development, LLC · NCT04132557
- PHASE4COMPLETEDNeuroimaging the Expectancy Versus Pharmacotherapy Effect of Adderall on Cognitive PerformanceUniversity of Alabama at Birmingham · NCT03530631
- PHASE2COMPLETEDNRP104, Adderall XR or Placebo in Children Aged 6-12 Years With ADHDNew River Pharmaceuticals · NCT00557011
- PHASE1COMPLETEDVyvanse and Adderall XR Given Alone and in Combination With Prilosec OTCShire · NCT00746733
~17 min read
Article
26 sectionsContents
- Uses
- Medical
- Attention Deficit Hyperactivity Disorder
- Narcolepsy
- Available forms
- Enhancing performance
- Recreational
- Contraindications
- Adverse effects
- Overdose
- Interactions
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Pharmacomicrobiomics
- Related endogenous compounds
- History
- Commercial formulation
- Comparison to other formulations
- Society and culture
- Legal status
- Names
- Shortages
- Notes
- Reference notes
- References
Adderall is the brand name of a fixed-dose combination medication used for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is also used as an athletic performance enhancer, cognitive enhancer, appetite suppressant, and recreationally as a euphoriant. Such uses are illegal in many countries. It is a central nervous system (CNS) stimulant of the phenethylamine class. It contains the amphetamines dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate. It is taken by mouth.
In therapeutic doses, Adderall causes emotional and cognitive effects such as euphoria, change in sex drive, increased wakefulness, and improved cognitive control. At these doses, it induces physical effects such as a faster reaction time, fatigue resistance, and increased muscle strength. In contrast, much larger doses of Adderall can impair cognitive control, cause rapid muscle breakdown, provoke panic attacks, or induce psychosis (e.g., paranoia, delusions, hallucinations). The side effects vary widely among individuals but most commonly include insomnia, dry mouth, loss of appetite and weight loss. The routine use of Adderall at higher-than-prescribed doses poses a significant risk of addiction or dependence due to the pronounced reinforcing effects that are present at high doses. Recreational doses of Adderall are generally much larger than prescribed therapeutic doses and also carry a far greater risk of serious adverse effects.