AIF1
Sign in to saveAlso known as AIF-1, IBA1, IRT-1, IRT1, allograft inflammatory factor 1, Iba-1
protein-coding gene in the species Homo sapiens
Gene data
AIF1- Name
- allograft inflammatory factor 1
- Type
- protein-coding
- Aliases
- AIF-1, IBA1, IRT-1, IRT1
This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016].
via MyGene.info
Gene · Ensembl
allograft inflammatory factor 1
- Symbol
- AIF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HSCHR6_MHC_QBL_CTG1:2,871,006-2,872,843
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein AIF1 PDB 2d58.png
Show 5 more facts
- HomoloGene ID
- 1226
- exact match
- identifiers.org/ncbigene/199
- genomic start
- 31615217
- genomic end
- 31584798
- cytogenetic location
- 6p21.33
Sources (3)
via Wikidata · CC0
Connections
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Ensembl genome database project
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