ALDH3A2
Sign in to saveAlso known as aldehyde dehydrogenase 3 family, member A2, ALDH10, FALDH, SLS, aldehyde dehydrogenase 3 family member A2
protein-coding gene in the species Homo sapiens
Gene data
ALDH3A2- Name
- aldehyde dehydrogenase 3 family member A2
- Type
- protein-coding
- Position
- 19,647,291–19,685,760 (+)
- Aliases
- ALDH10, FALDH, SLS
- Ensembl
- ENSG00000072210
- RefSeq RNA
- NM_000382.3, NM_001031806.2, NM_001369136.1, NM_001369137.2, NM_001369138.2
- RefSeq protein
- NP_000373.1, NP_001026976.1, NP_001356065.1, NP_001356066.1, NP_001356067.1
Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
3-chloroallyl aldehyde dehydrogenase activityaldehyde dehydrogenase (NAD+) activityaldehyde dehydrogenase (NAD+) activityaldehyde dehydrogenase (NAD+) activityaldehyde dehydrogenase (NAD+) activityprotein bindingoxidoreductase activityoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Pathways
Glycolysis / Gluconeogenesis - Homo sapiens (human)Ascorbate and aldarate metabolism - Homo sapiens (human)Fatty acid degradation - Homo sapiens (human)Valine, leucine and isoleucine degradation - Homo sapiens (human)Lysine degradation - Homo sapiens (human)Arginine and proline metabolism - Homo sapiens (human)Histidine metabolism - Homo sapiens (human)Tryptophan metabolism - Homo sapiens (human)beta-Alanine metabolism - Homo sapiens (human)Glycerolipid metabolism - Homo sapiens (human)
via MyGene.info
Gene · Ensembl
aldehyde dehydrogenase 3 family member A2
- Symbol
- ALDH3A2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:19,647,291-19,685,881
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 55458
- exact match
- identifiers.org/ncbigene/224
- genomic end
- 19685760
- genomic start
- 19551449
- cytogenetic location
- 17p11.2
via Wikidata · CC0
Connections
aldehydes
Entity
Q180686
Entity
nicotinamide adenine dinucleotide
Entity
active site
Entity
Ensembl genome database project
Entity
protein superfamily
Entity
oxygen
Entity
liver
Entity
enzyme
Entity
Wikidata
Entity
metabolism
Entity
chromosome
Entity
lipid
Entity
mitochondrion
Entity
digital object identifier
Entity
fatty acid
Entity
messenger RNA
Entity
triglyceride
Entity
bibcode
Entity
human genome
Entity