ALX1
Sign in to saveAlso known as CART1, FND3, HEL23, ALX homeobox 1
ALX homeobox protein 1 is a protein that in humans is encoded by the ALX1 gene.
Gene data
ALX1- Name
- ALX homeobox 1
- Type
- protein-coding
- Position
- 85,280,091–85,302,551 (+)
- Aliases
- CART1, FND3, HEL23
- Ensembl
- ENSG00000180318
- RefSeq RNA
- NM_006982.3
- RefSeq protein
- NP_008913.2
The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse gene lead to neural tube defects such as acrania and meroanencephaly. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
negative regulation of transcription by RNA polymerase IIregulation of DNA-templated transcriptionpositive regulation of epithelial to mesenchymal transitionnegative regulation of DNA-templated transcriptionpositive regulation of DNA-templated transcriptionpositive regulation of DNA-templated transcriptionpositive regulation of transcription by RNA polymerase IIpositive regulation of transcription by RNA polymerase II
Molecular function
RNA polymerase II transcription regulatory region sequence-specific DNA bindingRNA polymerase II transcription regulatory region sequence-specific DNA bindingDNA-binding transcription factor activity, RNA polymerase II-specificDNA-binding transcription factor activity, RNA polymerase II-specificDNA-binding transcription activator activity, RNA polymerase II-specificDNA-binding transcription activator activity, RNA polymerase II-specificDNA-binding transcription activator activity, RNA polymerase II-specificDNA binding
via MyGene.info
Gene · Ensembl
ALX homeobox 1
- Symbol
- ALX1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:85,280,091-85,302,551
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- References
- Further reading
- External links
ALX homeobox protein 1 is a protein that in humans is encoded by the ALX1 gene.
== Function ==
Excerpted from Wikipedia’s “ALX1” article, available under the CC BY-SA 4.0 licence.