
antitoxin
Sign in to saveAlso known as antitoxins
thumb|A vintage 1895 vial of diphtheria antitoxin.|252x252px
Research
16,310 papers- Toxin-Antitoxin Systems as Phage Defense Elements.Annual review of microbiology · 2022
- Biology and evolution of bacterial toxin-antitoxin systems.Nature reviews. Microbiology · 2022
- Toxin-antitoxin systems: Classification, biological roles, and applications.Microbiological research · 2022
- Antitoxin HigA orchestrates T3SS/T6SS expression in aquatic pathogen Edwardsiella piscicida.Microbiological research · 2025
- Antitoxin nanoparticles: design considerations, functional mechanisms, and applications in toxin neutralization.Drug discovery today · 2024
via PubMed
~3 min read
Article
5 sectionsContents
- History of antitoxin
- 21st-century serum therapy
- See also
- References
- External links
thumb|A vintage 1895 vial of diphtheria antitoxin.|252x252px
An antitoxin is an antibody with the ability to neutralize a specific toxin. Antitoxins are produced by certain animals, plants, and bacteria in response to toxin exposure. Although they are most effective in neutralizing toxins, they can also kill bacteria and other microorganisms. Antitoxins are made within organisms, and can be injected into other organisms, including humans, to treat an infectious disease. This procedure involves injecting an animal with a safe amount of a particular toxin. The animal's body then makes the antitoxin needed to neutralize the toxin. Later, blood is withdrawn from the animal. When the antitoxin is obtained from the blood, it is purified and injected into a human or other animal, inducing temporary passive immunity. To prevent serum sickness, it is often best to use an antitoxin obtained from the same species (e.g. use human antitoxin to treat humans).