antiserum
Also known as convalescent plasma treatment, immune serum, immune sera
In immunology, antiserum is a blood serum containing antibodies (either monoclonal or polyclonal) that is used to spread passive immunity to many diseases via blood donation (plasmapheresis). For example, convalescent serum, or passive antibody transfusion from a previous human survivor, was the only known effective treatment for Ebola infection with a high success rate of 7 out of 8 patients surviving.
Research
124,178 papers- The raising of a polyclonal antiserum to a protein.Methods in molecular biology (Clifton, N.J.) · 1994
- Antiserum for gram-negative bacteraemia.Lancet (London, England) · 1983
- Louping-ill antiserum.The Journal of comparative pathology and therapeutics · 1946
- EFFECTS OF ANTISERUM ON ADSORBED PHAGE.Journal of bacteriology · 1963
- CASTOR BEAN ANTISERUM.Bulletin (National Clearinghouse for Poison Control Centers (U.S.)) · 1964
via PubMed
Article
5 sectionsContents
- History
- Modern use
- How it works
- References
- External links
In immunology, antiserum is a blood serum containing antibodies (either monoclonal or polyclonal) that is used to spread passive immunity to many diseases via blood donation (plasmapheresis). For example, convalescent serum, or passive antibody transfusion from a previous human survivor, was the only known effective treatment for Ebola infection with a high success rate of 7 out of 8 patients surviving.
Antisera are widely used in diagnostic virology laboratories. The most common use of antiserum in humans is as antitoxin or antivenom to treat envenomation.