DRD5
Sign in to saveAlso known as DBDR, DRD1B, DRD1L2, dopamine receptor D5
protein-coding gene in the species Homo sapiens
Gene data
DRD5- Name
- dopamine receptor D5
- Type
- protein-coding
- Position
- 9,781,387–9,784,012 (+)
- Aliases
- DBDR, DRD1B, DRD1L2
- Ensembl
- ENSG00000169676
- RefSeq RNA
- NM_000798.5
- RefSeq protein
- NP_000789.1
This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
synaptic transmission, dopaminergicintracellular calcium ion homeostasisG protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwayadenylate cyclase-activating dopamine receptor signaling pathwayG protein-coupled dopamine receptor signaling pathwaychemical synaptic transmission
Molecular function
dopamine neurotransmitter receptor activity, coupled via Gsdopamine neurotransmitter receptor activity, coupled via Gsdopamine neurotransmitter receptor activity, coupled via GsG protein-coupled receptor activityG protein-coupled receptor activitydopamine neurotransmitter receptor activitydopamine neurotransmitter receptor activityprotein binding
Pathways
Calcium signaling pathway - Homo sapiens (human)cAMP signaling pathway - Homo sapiens (human)Neuroactive ligand-receptor interaction - Homo sapiens (human)Dopaminergic synapse - Homo sapiens (human)Signal TransductionSignaling by GPCRClass A/1 (Rhodopsin-like receptors)Amine ligand-binding receptorsGPCR downstream signallingDopamine receptors
via MyGene.info
Gene · Ensembl
dopamine receptor D5
- Symbol
- DRD5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:9,781,387-9,784,012
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 20216
- exact match
- identifiers.org/ncbigene/1816
- genomic end
- 9785632
- genomic start
- 9781634
- cytogenetic location
- 4p16.1
Sources (3)
via Wikidata · CC0
Available in 9 languages
via Wikidata sitelinks · CC0
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