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(6S)-rotigotine
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(6S)-rotigotine

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Also known as Leganto®, N-0437, Neupro®, Rotigotine, (6S)-6-(propyl(2-(2-thienyl)ethyl)amino)-5,6,7,8-tetrahydro-1-naphthalenol

Rotigotine, sold under the brand name Neupro among others, is a dopamine agonist of the non-ergoline class of medications indicated for the treatment of Parkinson's disease and restless legs syndrome. It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours.

Key facts

Drug.Verifiedfields
changed
Drug.verifiedrevid
464383949
Drug.image
Rotigotine.svg
Drug.image_class
skin-invert-image
Drug.image2
Rotigotine 3D-Structure Xtal.png
Drug.image_class2
bg-transparent
Drug.width2
271
Drug.tradename
Neupro, Leganto
Drug.MedlinePlus
a607059
Drug.DailyMedID
Rotigotine
Drug.pregnancy_AU
B3
Drug.routes_of_administration
Transdermal
Drug.ATC_prefix
N04
Drug.ATC_suffix
BC09
Drug.legal_AU
S4
Drug.legal_BR
C1
Drug.legal_US
Rx-only
Drug.legal_EU
Rx-only

via Wikipedia infobox

Research

1 papers

via PubMed

Wikidata facts

Mass
315.165685
Show 5 more facts
defined daily dose
6
chemical formula
C₁₉H₂₅NOS
canonical SMILES
CCCN(CCC1=CC=CS1)C2CCC3=C(C2)C=CC=C3O
isomeric SMILES
CCCN(CCC1=CC=CS1)[C@H]2CCC3=C(C2)C=CC=C3O
Commons category
Rotigotine
Sources (7)

via Wikidata · CC0

~4 min read

Article

5 sections
Contents
  • Side effects
  • Pharmacology
  • History
  • References
  • External links

Rotigotine, sold under the brand name Neupro among others, is a dopamine agonist of the non-ergoline class of medications indicated for the treatment of Parkinson's disease and restless legs syndrome. It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours.

Like other dopamine agonists, rotigotine has been shown to possess antidepressant effects and may be useful in the treatment of depression as well.

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