Structure via PubChem · Public domain (PubChem)
mosapramine
Sign in to saveMosapramine (Cremin) is an atypical antipsychotic used in Japan for the treatment of schizophrenia. It is a potent dopamine antagonist with high affinity to the D2, D3, and D4 receptors, and with moderate affinity for the 5-HT2 receptors.
In the Vinony graph
Vinony's link graph records 1,728 inbound references to mosapramine, and connects out to propranolol, fluphenazine and zuclopenthixol.
It sits within the topics Atypical antipsychotics, Chloroarenes and Dibenzazepines.
Vinony links it to 7 Wikipedia language editions.
Chemical data
- Formula
- C28H35ClN4O
- Molecular weight
- 479.1 g/mol
- IUPAC name
- 1'-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]spiro[1,5,6,7,8,8a-hexahydroimidazo[1,2-a]pyridine-3,4'-piperidine]-2-one
- SMILES
- C1CCN2C(C1)NC(=O)C23CCN(CC3)CCCN4C5=CC=CC=C5CCC6=C4C=C(C=C6)Cl
- InChIKey
- PXUIZULXJVRBPC-UHFFFAOYSA-N
- XLogP
- 5.4
- Polar surface area
- 38.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- psychosis
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 478.25
Show 3 more facts
- chemical formula
- C₂₈H₃₅ClN₄O
- canonical SMILES
- C1CCN2C(C1)NC(=O)C23CCN(CC3)CCCN4C5=CC=CC=C5CCC6=C4C=C(C=C6)Cl
- Commons category
- Mosapramine
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Mosapramine (Cremin) is an atypical antipsychotic used in Japan for the treatment of schizophrenia. It is a potent dopamine antagonist with high affinity to the D2, D3, and D4 receptors, and with moderate affinity for the 5-HT2 receptors.
== See also == Carpipramine Clocapramine Fluspirilene (typical antipsychotic) Imidazopyridine
Excerpted from Wikipedia’s “mosapramine” article, available under the CC BY-SA 4.0 licence.