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N-methylserotonin

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N-methylserotonin

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'''N-Methylserotonin, also known as norbufotenin or as 5-hydroxy-N-methyltryptamine (5-HO-NMT'), is a tryptamine alkaloid. Chemically, it is a derivative of serotonin in which a methyl group resides at its alkyl amine. It is also called Nω-methylserotonin (N''ω-methyl-5-hydroxytryptamine) to distinguish it from tryptamine-derived compounds in which a methyl group is bonded to the nitrogen atom of the indole group.

Chemical data

Formula
C11H14N2O
Molecular weight
190.24 g/mol
IUPAC name
3-[2-(methylamino)ethyl]-1H-indol-5-ol
SMILES
CNCCC1=CNC2=C1C=C(C=C2)O
InChIKey
ASUSBMNYRHGZIG-UHFFFAOYSA-N
XLogP
0.7
Polar surface area
48.1 Ų
H-bond donors
3
H-bond acceptors
2
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
190.110613
Show 3 more facts
found in taxon
tomato
chemical formula
C₁₁H₁₄N₂O
canonical SMILES
CNCCC1=CNC2=C1C=C(C=C2)O
Sources (2)

via Wikidata · CC0

~2 min read

Encyclopedic overview

10 sections
Contents
  • Pharmacology
  • Pharmacodynamics
  • Chemistry
  • Analogues
  • Society and culture
  • Legal status
  • United States
  • Florida
  • See also
  • References

'''N-Methylserotonin, also known as norbufotenin or as 5-hydroxy-N-methyltryptamine (5-HO-NMT'), is a tryptamine alkaloid. Chemically, it is a derivative of serotonin in which a methyl group resides at its alkyl amine. It is also called Nω-methylserotonin (Nω-methyl-5-hydroxytryptamine) to distinguish it from tryptamine-derived compounds in which a methyl group is bonded to the nitrogen atom of the indole group.

N-Methylserotonin is found in plants, animals, and fungi. These include the plants, Actaea racemosa (black cohosh) and Zanthoxylum piperitum, the Green and Golden Bell Frog, Litoria aurea, and Amanita mushrooms.

Excerpted from Wikipedia’s “N-methylserotonin” article, available under the CC BY-SA 4.0 licence.

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