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Pyr-T

Structure via PubChem · Public domain (PubChem)

EntityQ7263202· pop 7· linked from 1,002 articles

Pyr-T, also known as '''N,N-tetramethylenetryptamine or as 3-(2-pyrrolidinoethyl)indole', is a lesser-known serotonin receptor modulator of the tryptamine and pyrrolidinylethylindole families. It is the cyclized derivative of diethyltryptamine (DET) in which the N,N''-diethyl groups have been fused into a pyrrolidine ring.

In the Vinony graph

Within Vinony's link graph, Pyr-T is referenced by 1,002 other articles, and connects out to tryptamines, N-methylserotonin and 5-HT receptor.

It sits within the topics 1-Pyrrolidinyl compounds, Chemical pages without DrugBank identifier and Drugs not assigned an ATC code.

Its subject is documented across 6 Wikipedia language editions.

Chemical data

Formula
C14H18N2
Molecular weight
214.31 g/mol
IUPAC name
3-(2-pyrrolidin-1-ylethyl)-1H-indole
SMILES
C1CCN(C1)CCC2=CNC3=CC=CC=C32
InChIKey
CVTZCBLFHNGYDQ-UHFFFAOYSA-N
XLogP
3
Polar surface area
19 Ų
H-bond donors
1
H-bond acceptors
1
Formal charge
0

via PubChem

Wikidata facts

Mass
214.146999
Show 3 more facts
chemical formula
C₁₄H₁₈N₂
canonical SMILES
C1CCN(C1)CCC2=CNC3=CC=CC=C32
Commons category
Pyr-T
Sources (2)

via Wikidata · CC0

~3 min read

Encyclopedic overview

11 sections
Contents
  • Use and effects
  • Interactions
  • Pharmacology
  • Pharmacodynamics
  • Chemistry
  • Synthesis
  • Analogues
  • History
  • See also
  • References
  • External links

Pyr-T, also known as '''N,N-tetramethylenetryptamine or as 3-(2-pyrrolidinoethyl)indole', is a lesser-known serotonin receptor modulator of the tryptamine and pyrrolidinylethylindole families. It is the cyclized derivative of diethyltryptamine (DET) in which the N,N-diethyl groups have been fused into a pyrrolidine ring.

==Use and effects== In his 1997 book TiHKAL (Tryptamines I Have Known and Loved), Alexander Shulgin reported neither the dose range nor the duration of the drug. However, individual experiments employed 25 to 50mg orally and 70mg smoked. Pyr-T produced effects including malaise, feeling sick, unpleasantness, salivation, muscle and joint pains, dizziness, feeling high, and uncomfortableness. Hallucinogenic effects, for instance visuals, were either absent or minor.

Excerpted from Wikipedia’s “Pyr-T” article, available under the CC BY-SA 4.0 licence.

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