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EntityQ7263194· pop 5· linked from 2 articles

Pyr1 (LIMINIB) is an organic compound composed of carbon, hydrogen, oxygen and nitrogen that inhibits the enzyme LIM kinase.

Wikidata facts

Mass
382.13174243599997
Show 3 more facts
canonical SMILES
O=C(C1=CC=CC=C1)OC(C=C2)=CC3=C2NC4=C3C(C)=C5C(C=CNC5=O)=C4C
chemical formula
C₂₄H₁₈N₂O₃
Commons category
Pyr1
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Article

5 sections
Contents
  • Description and properties
  • Mechanism of action
  • Medical applications
  • References
  • External links

Pyr1 (LIMINIB) is an organic compound composed of carbon, hydrogen, oxygen and nitrogen that inhibits the enzyme LIM kinase.

It was discovered by the Cure and Inserm Institute, CNRS and CEA in the 2010s. The studies in vitro and with animals, prove that this molecule has a completely new mechanism of action that could be used against chemotherapy resistant cells.

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