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Pyr1
Sign in to savePyr1 (LIMINIB) is an organic compound composed of carbon, hydrogen, oxygen and nitrogen that inhibits the enzyme LIM kinase.
In the Vinony graph
Within Vinony's link graph, Pyr1 is referenced by 2 other articles, and connects out to protein, enzyme and chromosome.
It is catalogued under topics including Benzoate esters, Carbazoles and Chembox image size set.
Its subject is documented across 4 Wikipedia language editions.
Chemical data
- Formula
- C24H18N2O3
- Molecular weight
- 382.4 g/mol
- IUPAC name
- (5,11-dimethyl-1-oxo-2,6-dihydropyrido[4,3-b]carbazol-9-yl) benzoate
- SMILES
- CC1=C2C=CNC(=O)C2=C(C3=C1NC4=C3C=C(C=C4)OC(=O)C5=CC=CC=C5)C
- InChIKey
- BPGBAEXPBQHBSV-UHFFFAOYSA-N
- XLogP
- 4.9
- Polar surface area
- 71.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 382.13174243599997
Show 3 more facts
- canonical SMILES
- O=C(C1=CC=CC=C1)OC(C=C2)=CC3=C2NC4=C3C(C)=C5C(C=CNC5=O)=C4C
- chemical formula
- C₂₄H₁₈N₂O₃
- Commons category
- Pyr1
Sources (2)
via Wikidata · CC0
~4 min read
Encyclopedic overview
5 sectionsContents
- Description and properties
- Mechanism of action
- Medical applications
- References
- External links
Pyr1 (LIMINIB) is an organic compound composed of carbon, hydrogen, oxygen and nitrogen that inhibits the enzyme LIM kinase.
It was discovered by the Cure and Inserm Institute, CNRS and CEA in the 2010s. The studies in vitro and with animals, prove that this molecule has a completely new mechanism of action that could be used against chemotherapy resistant cells.
Excerpted from Wikipedia’s “Pyr1” article, available under the CC BY-SA 4.0 licence.