Skip to content
EntityQ2394183· pop 14· linked from 2,428 articles

etryptamine

Sign in to save

Also known as α-ethyltryptamine, αET, alpha-ethyltryptamine, 3-(2-aminobutyl)indole

α-Ethyltryptamine (αET, AET), also known as etryptamine, is an entactogen and stimulant drug of the tryptamine family. It was originally developed and marketed as an antidepressant under the brand name Monase by Upjohn in the 1960s before being withdrawn due to toxicity.

Key facts

Drug.verifiedrevid
447115140
Drug.drug_name
α-Ethyltryptamine
Drug.INN
Etryptamine
Drug.USAN
Etryptamine
Drug.image
AET.svg
Drug.image_class
skin-invert-image
Drug.width
200px
Drug.image2
Alpha-Ethyltryptamine-3d-sticks.png
Drug.image_class2
bg-transparent
Drug.width2
235px
Drug.tradename
Monase
Drug.routes_of_administration
Oral
Drug.class
Entactogen; Stimulant; Monoamine releasing agent; Serotonin receptor agonist; Monoamine oxidase inhibitor
Drug.legal_BR
F2
Drug.legal_CA
Schedule III
Drug.legal_US
Schedule I
Drug.legal_UK
Class A
Drug.legal_DE
Anlage I

via Wikipedia infobox

Wikidata facts

Mass
188.131349
Show 4 more facts
chemical formula
C₁₂H₁₆N₂
World Health Organisation international non-proprietary name
etryptamine
canonical SMILES
CCC(CC1=CNC2=CC=CC=C21)N
Commons category
Alpha-Ethyltryptamine
Sources (2)

via Wikidata · CC0

~12 min read

Article

22 sections
Contents
  • Use and effects
  • Side effects
  • Overdose
  • Interactions
  • Pharmacology
  • Pharmacodynamics
  • Pharmacokinetics
  • Chemistry
  • Synthesis
  • Analogues
  • History
  • Society and culture
  • Names
  • Recreational use
  • Legal status
  • Canada
  • United Kingdom
  • United States
  • Research
  • See also
  • References
  • External links

α-Ethyltryptamine (αET, AET), also known as etryptamine, is an entactogen and stimulant drug of the tryptamine family. It was originally developed and marketed as an antidepressant under the brand name Monase by Upjohn in the 1960s before being withdrawn due to toxicity.

Side effects of αET include facial flushing, headache, gastrointestinal distress, insomnia, irritability, appetite loss, and sedation, among others. A rare side effect of αET is agranulocytosis. αET acts as a releasing agent of serotonin, norepinephrine, and dopamine, as a weak serotonin receptor agonist, and as a weak monoamine oxidase inhibitor. It may also produce serotonergic neurotoxicity. αET is a substituted tryptamine and is closely related to α-methyltryptamine (αMT) and other α-alkylated tryptamines.

Connections

Categories