Structure via PubChem · Public domain (PubChem)
zolmitriptan
Sign in to saveAlso known as (S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one, 4-{[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl}oxazolidin-2-one, 4-{[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]methyl}oxazolidin-2-one
Zolmitriptan, sold under the brand name Zomig among others, is a serotonergic medication which is used in the acute treatment of migraine attacks with or without aura and cluster headaches. It is taken by mouth as a swallowed or disintegrating tablet or as a nasal spray.
Chemical data
- Formula
- C16H21N3O2
- Molecular weight
- 287.36 g/mol
- IUPAC name
- (4S)-4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1,3-oxazolidin-2-one
- SMILES
- CN(C)CCC1=CNC2=C1C=C(C=C2)C[C@H]3COC(=O)N3
- InChIKey
- ULSDMUVEXKOYBU-ZDUSSCGKSA-N
- XLogP
- 2.2
- Polar surface area
- 57.4 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
730 papers- Zolmitriptan.2006
- Zolmitriptan.2026
- Intranasal zolmitriptan.Expert opinion on pharmacotherapy · 2005
- Zolmitriptan (Zomig).Expert review of neurotherapeutics · 2004
- Zolmitriptan: a review of its use in migraine.Drugs · 1999
via PubMed
Wikidata facts
- Mass
- 287.163377
Show 7 more facts
- chemical formula
- C₁₆H₂₁N₃O₂
- canonical SMILES
- CN(C)CCC1=CNC2=C1C=C(C=C2)CC3COC(=O)N3
- isomeric SMILES
- CN(C)CCC1=CNC2=C1C=C(C=C2)C[C@H]3COC(=O)N3
- World Health Organisation international non-proprietary name
- zolmitriptan
- stylized name
- ZOLMitriptan
- Commons category
- Zolmitriptan
- defined daily dose
- 2.5
via Wikidata · CC0
~12 min read
Article
28 sectionsContents
- Medical uses
- Migraine
- Off-label uses
- Available forms
- Contraindications
- Side effects
- Overdose
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Absorption
- Distribution
- Metabolism
- Elimination
- Chemistry
- History
- Society and culture
- Brand names
- Economics
- Legal status
- Research
- Obsessive–compulsive disorder
- Social deficits and aggression
- See also
- References
- Further reading
- External links
{{Drugbox | Watchedfields = verified | verifiedrevid = 477869605 | IUPAC_name = (S)-4-({3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one | image = Zolmitriptan.svg | image_class = skin-invert-image | width = 250px | image2 = Zolmitriptan_3D_Ball.png | image_class2 = bg-transparent | width2 = 225px
| tradename = Zomig, others | Drugs.com = | MedlinePlus = a601129 | DailyMedID = Zolmitriptan | pregnancy_AU = B3 | routes_of_administration = By mouth, intranasal | class = Serotonin 5-HT1B, 5-HT1D, 5-HT1E, and 5-HT1F receptor agonist; Antimigraine agent; Triptan