Pellotine
Sign in to savePellotine, also known as peyotline or '''N-methylanhalonidine', is a tetrahydroisoquinoline alkaloid found in Lophophora species, in particular L. diffusa. It is the second most common alkaloid found in Lophophora williamsii'' (peyote). Pellotine is slightly sedative, and has been used by Native Americans as a constituent of peyote for sacramental purposes. It was reportedly once marketed for use as a sedative. Pellotine has been sold online.
Wikidata facts
- Mass
- 237.136493
Show 2 more facts
- canonical SMILES
- CC1C2=C(C(=C(C=C2CCN1C)OC)OC)O
- chemical formula
- C₁₃H₁₉NO₃
Sources (1)
via Wikidata · CC0
~2 min read
Article
5 sectionsContents
- Pharmacology and effects
- Ancient use
- See also
- References
- External links
Pellotine, also known as peyotline or '''N-methylanhalonidine', is a tetrahydroisoquinoline alkaloid found in Lophophora species, in particular L. diffusa. It is the second most common alkaloid found in Lophophora williamsii (peyote). Pellotine is slightly sedative, and has been used by Native Americans as a constituent of peyote for sacramental purposes. It was reportedly once marketed for use as a sedative. Pellotine has been sold online.
== Pharmacology and effects == Doses of 8 to 10mg of isolated pellotine are known to cause convulsions in frogs. When injected subcutaneously to humans, participants have reported drowsiness and a desire not to exert any physical or mental effort, with one study reporting it to have hypnotic effects. It is also reported to lower blood pressure and heart rate. Pellotine produced no hallucinogenic effects in humans at doses of up to 250mg. However, it has been reported to have a calming or sedative effect instead.