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amfecloral
Sign in to saveAlso known as Amphecloral
Amfecloral (INN) or amphecloral (USAN) is a combination drug containing a central nervous system (CNS) stimulant and anorectic drug, dextroamphetamine, as well as a CNS depressant and sedative-hypnotic, chloral hydrate.
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 263.003532424
- Has use
- medication
Show 3 more facts
- chemical formula
- C₁₁H₁₂Cl₃N
- canonical SMILES
- CC(CC1=CC=CC=C1)\N=C\C(Cl)(Cl)Cl
- Commons category
- Amfecloral
Sources (2)
via Wikidata · CC0
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Encyclopedic overview
8 sectionsContents
- Naming and Classification
- Synthesis and Pharmacology
- History
- Combination Drugs in the Twentieth Century
- Efficacy and Tolerability
- Discontinuation
- See also
- References
Amfecloral (INN) or amphecloral (USAN) is a combination drug containing a central nervous system (CNS) stimulant and anorectic drug, dextroamphetamine, as well as a CNS depressant and sedative-hypnotic, chloral hydrate.
Widely used for its anorectic properties, amfecloral was approved by the United States Food and Drug Administration as an anti-obesity drug and marketed and distributed under the brand name Acutran. Upon 1962 passage of the Kefauver-Harris Amendment, pressure grew to withdraw the product from the market, and in 1973, production ceased for Acutran and its generic formulation, concurrent with similar combination anorectics, Desbutal (methamphetamine-pentobarbital) and Obetrol (methamphetamine-dextroamphetamine).
Excerpted from Wikipedia’s “amfecloral” article, available under the CC BY-SA 4.0 licence.